EPL Predictions Week 2: Previews, Best Bets, and Analysis

We saw surprising stumbles from a couple of the biggest names over opening weekend. Our EPL predictions for week 2 look at what's in store for the big boys in England's top flight.

Premier League Predictions Week 2: Recommended Bets

Contrasting Start For Top Clubs

What a start to the 2022-23 Premier League season! Newly promoted teams outperformed predictions, favored teams fell short, and Haaland, like the mailman, delivered as expected. On the heels of a great opening weekend, there's an awful lot to look forward to on Gameday 2.

A London derby between Tottenham and Chelsea on Sunday is the pick of the fixtures, while Erik Ten Hag's Manchester United head to Brentford, hoping to bounce back from a home defeat to Brighton in their opener.

The first weekend gave us a glimpse of what these teams will look like early this season and informed our EPL predictions for Week 2. Having pored over the best EPL odds, here are our top three picks. 

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EPL Predictions Week 2:

Leicester @ Arsenal

Saturday, August 13 at 10:00 a.m. ET

Arsenal and Leicester each face an early season test on Saturday when the sides meet at the Emirates in one of the weekend's marquee fixtures. Leicester comes into this one off the back of a disappointing 2-2 home draw with Brentford, in which they let a 2-0 lead slip in the game's final half hour. Nonetheless, the Foxes have the quality to make life difficult for Arsenal. 

While Arsenal's attack was not at its potent best against Crystal Palace, the Gunners' front line should be able to create chances facing a Leicester defense that had the fourth-fewest clean sheets (seven) in the league last season. Only Leeds, Watford, and Norwich allowed more expected goals than the Foxes (61 xGA) in 2021-22. 

Additionally, there were over 2.5 goals in 63% of Leicester's games in 2021-22 (second highest in the league). Backing the Over is always a good wager with Brendan Rodgers' teams, even at a short price. 

Premier League Best Bets: Best EPL Odds

Manchester United @ Brentford

Saturday, August 13 at 12:30 p.m. ET

Despite being outplayed by Brighton at Old Trafford last weekend, Manchester United are still favorites for their trip to Brentford. 

It should be mentioned that Brentford, in racking up 24 of their 46 points last season at home, defeated Arsenal and West Ham and held Liverpool and Tottenham to draws at the Brentford Community Stadium last season and, of course, dished out a 4-1 hammering to Chelsea at Stamford Bridge in early April. 

Ten Hag has a lot of work to do with this Man United side. The midfield was exposed against Brighton. Eyeing new signings like Adrien Rabiot gives some hope, but will be too late ahead of the game on Saturday. And, of course, the uncertainty surrounding Cristiano Ronaldo continues to loom over the attack. 

Looking through the best EPL odds, FanDuel's +250 on a draw offers the best value. Brentford has shown they can take points off the top sides, and the Red Devils, though motivated, have shown a propensity for surrendering points for some time now. Given their inconsistency, it's hard to have any real confidence these days in Man United winning away from home, let alone as a short favorite (+100). 

Premier League Best Bets: Best EPL Odds

Tottenham @ Chelsea

Sunday, August 14 at 11:30 a.m. ET

Tottenham lived up to preseason expectations with a 4-1 opening weekend thrashing of Southampton. However, Antonio Conte's team is still underdogs for their trip to Chelsea on Sunday. 

This is despite an uninspiring performance from Thomas Tuchel's Blues to start the season, in which they ground out a 1-0 win over Everton. An away win to start the season is a hugely positive result and even more so, beating the Toffees for the first time since 2017 at Goodison Park. Still, Chelsea's attack lacked firepower throughout the game and needed a first-half stoppage time penalty from Jorginho to secure the points by the narrowest of margins. 

If that performance is indicative of where Chelsea is, the hosts simply do not have the attack to go toe-to-toe with Tottenham, who started the season in fine goal-scoring form, even without Harry Kane or Heung-min Son getting on the score sheet. Harry Kane will want to hit a good run of form soon, otherwise, questions may be asked ahead of the 2022 World Cup

This matchup is never dull, and it's a safe bet that this meeting will be another fiery one. Spurs to win on Sunday is one of our top EPL predictions for Week 2! 

Premier League Best Bets: Best EPL Odds

Frequently Asked Question (FAQ):

What are this week's Premier League fixtures? 

There is another full fixture schedule on gameday 2, spread across three days.

Saturday, August 13th: 

  • Everton @ Aston Villa 
  • Leicester @ Arsenal
  • Newcastle @ Brighton
  • AFC Bournemouth @ Man City
  • Leeds @ Southampton
  • Fulham @ Wolves
  • Man Utd @ Brentford

Sunday, August 14th: 

  • West Ham @ Nottingham Forest
  • Spurs @ Chelsea

Monday, August 15th

  • Crystal Palace @ Liverpool


Teams are going to have a point to prove, who are you backing in matchweek 2? We saw surprising stumbles from a couple of the biggest names over opening weekend. Our EPL predictions for week 2 look at what's in store for the big boys in England's top flight.If you're looking for more soccer content, read our guide: How To Bet on Soccer, and visit our odds comparison tool to compare the latest odds.