NFLGame PreviewsDEN VS IND Preview Week2 season 14-SEP-2025

Game Preview of Denver Broncos @ Indianapolis Colts. Week 2 of 2025 NFL Season

DEN logo

DEN

1-0-0
@
14SEP25
04:05pm
IND logo

IND

1-0-0
Lucas Oil Stadium, Indianapolis, IN

Game Preview

The Broncos visit Lucas Oil Stadium on Sunday, 14 September (1:00 PM ET) to face the Colts. Denver brings a defence that smothers big plays and turns pressure into sacks. Indianapolis counters with an offence that flashed pace and balance in Week 1, plus a defence that took the ball away.

 

Sean Payton said he wants more balance after a pass-heavy opener. That fits the matchup. Indy’s front has several key players listed questionable, and the Colts’ run defence has leaked chunk gains in a small sample. Expect J.K. Dobbins and RJ Harvey to set up easier throws for Bo Nix.

 

On the other side, Daniel Jones steps into a tougher test. Denver ranks elite in pressure-to-sack rate and in limiting explosive passes. If Indy’s receivers can’t uncover quickly, especially with Josh Downs questionable, long drives may stall.

 

One wild card is the Colts’ banged-up secondary. Charvarius Ward and Jaylon Jones are both questionable. If either sits or is limited, Courtland Sutton and rookie Troy Franklin get cleaner looks on the perimeter. That could be the opening Denver needs in a game with a modest total ladder.

Current Season Form

DEN logo

DEN

Away
Record:1-0-0
ATS:0-1-0
O/U:0-1-0
IND logo

IND

Home
Record:1-0-0
ATS:1-0-0
O/U:0-1-0

Head-to-Head Summary

Record:
3-2Winner logo
ATS:4-1-0
O/U:2-3-0

Past Results

DateOpponentResultATSO/U
2025-09-07vs MIAW 33-8W +1.5u47.5
2025-01-05vs JAXW 26-23W +3.5o45.5
2024-12-29@ NYGL 33-45L -7.5o40.5
2024-12-22vs TENW 38-30W +4.0o42.5
2024-12-15@ DENL 13-31L 4.5o43.5
2024-12-01@ NEW 25-24W +-2.5o41.5
2024-11-24vs DETL 6-24L -7.0u50.5
2024-11-17@ NYJW 28-27L 4.0o43.0
2024-11-10vs BUFL 20-30L -4.5o46.5
2024-11-03@ MINL 13-21L 6.5u47.0

Key Insights

 

  • Denver allows just 3.0% explosive passes (84th percentile; sample 33).

  • Denver converts 15.2% of pressures into sacks (100th percentile; sample 33).

  • Colts generate takeaways at a 6.5% rate (100th percentile; sample 46).

  • Indy defence has multiple front-seven starters/questionables (Buckner, Paye, Ebukam).

  • Colts’ run defence has allowed a 16.7% explosive run rate (small sample 12).

  • Third-down swing: Denver’s stop rate is 85.7% (100th percentile; small sample 14).

 

 

Betting Insights

 

  • Spread lean: Broncos -3.0 (+106). Plus-money on a defence that finishes pressure; variance higher at a key number.

  • Total view: The 47.0 Under is heavily juiced (-222). If you want a fairer hold, Under 43.5 (-139) matches the defensive profile but at more reasonable risk.

  • Courtland Sutton Anytime TD (+162): Indy CBs Ward/Jaylon Jones are questionable; Denver’s WR1 should see high-leverage targets.

  • J.K. Dobbins Over 46.5 rushing yards (-118): Colts’ explosive run allowed rate (16.7%; small sample) and front-seven Qs point to ground success.

  • Bo Nix Under 223.5 passing yards (-119): Indy limits explosives (3.2%; sample 31) and leads in turnover rate (6.5%).

  • Michael Pittman Jr. Under 43.5 receiving yards (-116): Denver’s pass defence caps chunk plays and finishes pressure.

 

 

Final Summary

This sets up as a trenches matchup. Denver’s defence wins with efficiency: tight coverage, quick sacks, and third-down stops. If the Broncos run game gets on schedule, they can play from ahead and protect Nix with play-action.

Indianapolis still has paths. The Colts create takeaways and can pop runs with Jonathan Taylor. If Jones keeps the ball out quickly and they stay on script, Indy can grind drives and keep the Denver pass rush honest.

Injuries may swing this. If the Colts’ secondary is short-handed, Sutton and Franklin can punish single coverage. If Buckner and Co. are limited, Denver’s run game gets a real boost.

Our card leans Broncos -3 (+106) and a defensive game state overall, with preference to Unders on select receiver numbers and a ground-heavy plan for Denver. As always, note the juice and the sample sizes early in the season. Keep stake sizes modest and be ready to adjust if the Colts’ inactives break in their favour.

Statistical Battle Boards

Viewing: IND Offense vs DEN Defense
Offense team logoOffense
Defense team logoDefense
StatisticOffenseRankDefenseRankAdvantage
Total Points33#412#28IND advantage
Total Points Per Game33#412#5IND advantage
Total Touchdowns3#50#1DEN advantage
Passing Touchdowns1#170#2DEN advantage
Rushing Touchdowns2#70#11IND advantage
Other Touchdowns0#30#30IND advantage
Total Kicking Points15#112#3IND advantage
Total Two Point Conversions0#50#6IND advantage
Kick Extra Points3#70#31IND advantage
Offense team logoOffense
Defense team logoDefense
StatisticOffenseRankDefenseRankAdvantage
Net Passing Yards262#862#32IND advantage
Net Passing Yards Per Game262#862#32IND advantage
Passer Rating116#654.5#31IND advantage
Passing Attempts29#2128#9DEN advantage
Completions22#1312#32IND advantage
Completion Percentage75.9#342.9#1DEN advantage
Passing 1st downs14#75#1DEN advantage
Passing 1st Down %51.9#2071.4#25IND advantage
Longest Pass36#1229#21IND advantage
Passing Fumbles Lost0#291#3DEN advantage
Receiving Targets29#1925#25IND advantage
Receptions22#1312#1DEN advantage
Receiving Yards After Catch112#1164#7DEN advantage
YAC Average5.1#105.3#26IND advantage
Offense team logoOffense
Defense team logoDefense
StatisticOffenseRankDefenseRankAdvantage
Rushing Yards156#671#8IND advantage
Rushing Yards Per Game156#671#25IND advantage
Rushing Attempts40#121#5IND advantage
Yards Per Rush Attempt3.9#173.4#20IND advantage
Rushing 1st downs11#32#3🏈
20+ Yard Rushing Plays0#270#27🏈
Long Rushing15#189#28IND advantage
Rushing Fumbles0#270#27🏈
Rushing Fumbles Lost0#51#4DEN advantage