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Barnes runs 14.8 drives per game and generates 7.0 drive points per night at the rim. That creation is gone. Leonard operates at a 30.3% usage rate and demands defensive attention on every possession. When those two disappear from a lineup, you do not just lose points, you lose the reads and pressure that create easy shots for everyone else. RJ Barrett now carries this offense alone, and his road is steep. He drives into one of the toughest defensive matchups on Toronto's schedule with heavy legs after a loss in Boston last night. The Philadelphia 76ers defense ranks 7th in the league with a 109.0 defensive rating, and Tyrese Maxey is waiting on the other end, driving 15.9 times per game at 55.7% drive field-goal percentage for 11.9 drive points per night. Same game, completely different positions.
The major uncertainty hanging over all of this is the Philadelphia injury report. Joel Embiid (foot) and LeBron James (back) are both listed questionable. That matters enormously. With both healthy, Philadelphia's offensive ceiling is high and Toronto's path to competitiveness narrows fast. If both sit, Maxey and Jaylen Brown absorb the load, Philly's own scoring dips, and the spread conversation opens up. The market has priced this near a coin flip at Raptors +10.0 precisely because of that uncertainty, and the sharp money is watching those injury designations closely before tip.
Philadelphia owns a 4-2 home record this season, scoring 109.8 points per game at Xfinity Mobile Arena. Toronto enters on a two-game losing streak with a 3-3 road record and 114.3 road points per game when healthy. That version of this Raptors team no longer exists tonight. Barrett, Immanuel Quickley, and Ja'Kobe Walter are the weapons. What happens before tip will determine how much damage they can limit.
Picks made November 12, 2026 at 06:24 AM ET. Odds shown reflect current market prices.
The honest caveat is the injury report. If Embiid and LeBron both dress and both play their usual minutes, this game could get away from Toronto quickly. The spread and Under both become harder to hit if Philadelphia runs their full lineup at full strength against a skeleton Raptors unit on a back-to-back. The LeBron assists prop depends entirely on him suiting up. Watch the injury designations before tip. The best plays tonight are the ones that do not depend on that answer: Barrett's usage increase happens whether Philly runs their full lineup or not, and the Under is structurally sound in any Embiid and LeBron scenario because Toronto's ceiling is capped regardless. Build your ticket around those two anchors and size accordingly. For more picks, check out our NBA picks today and first basket picks.
Toronto Raptors vs Philadelphia 76ers predictions: Barnes and Leonard out, Under 221.0 our best bet. Barrett Over 19.5 at -189 is the top prop.