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MLBGame PreviewsSt. Louis Cardinals at Detroit Tigers
St. Louis CardinalsSt. Louis Cardinals
@
Comerica Park
Detroit TigersDetroit Tigers

Match Predictor

Pre-match Prediction
St. Louis Cardinals
@
Detroit Tigers
St. Louis Cardinals 41%Detroit Tigers 59%
Market LinesRun Line: Detroit Tigers -1Total: O/U 7.5
Model: Under 7.5
Model projects 7.3 total runs vs 7.5 line

St. Louis Cardinals

0022446688101012121414OVERUNDERO/U 7.5Runs ScoredRuns Allowed
All Over 7.5
43%
3/7
MLB: 48%
Starter
100%
1/1
vs DET
0%
0/1
Avg Total
8.7
MLB: 8.9
Game Starter (1) Last Starter vs DET vs DET (1)
Dustin May #3 · RHP · Age 29
13.50
ERA (2026)
6.8
K/9 (2026)
1
Starts (2026)
18.0
Avg Total (2026)
Last 3:
L TB (Mar 29): 4.0IP, 6ER, 3K
ND CLE (Sep 03): 3.0IP, 1ER, 1K
L PIT (Aug 30): 5.1IP, 6ER, 5K
Bullpen (2026 Season)Average
ERA: 4.13MLB Avg: 3.958 relievers
Workload Alert: Allowed 11 runs on 2026-03-29 vs TB. Bullpen arms likely still recovering.
Recent: L 7-11L 2-4W 3-0W 2-1L 0-4
Lineup vs Dustin May (Career)
BatterPosPAAVGOPSHR
Jahmai JonesRF2.10002.0000
12 batters with no matchup history

Detroit Tigers

0022446688101012121414OVERUNDERO/U 7.5Runs ScoredRuns Allowed
All Over 7.5
43%
3/7
MLB: 48%
Starter
0%
0/1
vs STL
0%
0/1
Avg Total
7.4
MLB: 8.9
Game Starter (1) Last Starter vs STL vs STL (1)
Jack Flaherty #9 · RHP · Age 31
4.15
ERA (2026)
4.4
K/9 (2026)
1
Starts (2026)
3.0
Avg Total (2026)
Last 3:
L @SD (Mar 28): 4.1IP, 2ER, 2K
ND @SEA (Oct 10): 2.0IP, 0ER, 2K
L SEA (Oct 07): 3.1IP, 3ER, 6K
vs STL: ND (Apr 30 2024): 6.2 IP, 0 ER, 14 K
Bullpen (2026 Season)Poor
ERA: 4.95MLB Avg: 3.958 relievers
Workload Alert: Allowed 9 runs on 2026-03-30 vs ARI. Bullpen arms likely still recovering.
Recent: L 0-3L 6-9L 5-7L 0-1W 4-0
Lineup vs Jack Flaherty (Career)
BatterPosPAAVGOPSHR
Alec Burleson1B2.0000.0000
Ivan HerreraC2.5001.0000
Masyn WinnSS2.0000.0000
Nolan Gorman2B2.0000.0000
Ramon Urias3B2.5002.5001
8 batters with no matchup history
Our Top PicksLive Odds
Top PickUnder 7.5 runs (-120, MEDIUM confidence)
Our model projects 7.3 combined runs, and the environment does the rest.
PickCardinals +1.5 run line (-172, LOW confidence)
The model projects a 4.1-3.2 final, a 0.9-run margin.
PickCardinals moneyline (+124, LOW confidence, contrarian)
The market prices Detroit at -179, implying 64.1% win probability.

St. Louis Cardinals vs Detroit Tigers Game Preview

The story of tonight's MLB matchup at Comerica Park starts with one number: 13.50. That is Dustin May's ERA through one 2026 start, a four-inning disaster against Tampa Bay where he surrendered six earned runs and 10 hits. He struck out three. For a pitcher whose value depends on weak contact and sink, those numbers signal something structural, not situational. Across his last three outings, May has posted strikeout totals of 3, 1, and 5. He is pitching to contact because his fastball command has forced it. The Detroit Tigers lineup, stacked with left-handed bats, was built to punish pitchers in exactly that situation.

Jack Flaherty counters from the home side, and he carries his own questions into tonight. His only 2026 start lasted 4.1 innings in San Diego, producing two earned runs and four walks against two strikeouts. The command issues are real. But context separates Flaherty from May in a meaningful way. His lone career regular-season appearance against the St. Louis Cardinals, on April 30, 2024, produced 6.2 shutout innings and 14 strikeouts. That version of Flaherty exists. And Comerica Park, carrying a 0.97 runs factor and a 0.92 home run factor, pushes this game toward the lower end of any scoring range by design. Spacious outfield, pitcher-friendly angles. This is not a park that hands out crooked numbers.

The individual matchup that shapes the first half of this game is Kevin McGonigle against May. The Tigers shortstop is posting a .945 OPS against right-handed pitching this season, slashing .346/.414/.538. As one analyst noted: "Across his first 18 at-bats against righties, the Tigers rookie has six hits, two doubles, and a triple." He bats left-handed against a pitcher with documented platoon vulnerability, and another analyst added: "May has pretty stark platoon splits, which should make him uber-vulnerable against the left-handed Kevin McGonigle." Colt Keith follows with a similar profile. Keith is slashing .364 with a 1.037 OPS over the last seven days and a .545 slugging percentage on the season. Two dangerous left-handed bats in a row facing a starter who cannot trust his fastball. That is not a comfortable position for May.

The contrarian angle worth taking seriously involves the moneyline. The market has priced St. Louis down to +124, reacting heavily to one May start. But the Cardinals are 4-3 overall and 2-0 in extra innings. Their bullpen carries a 4.13 ERA. Flaherty's own 2026 velocity and command entering tonight raises genuine questions about how dominant Detroit actually is. Our model assigns Detroit a 58.9% win probability. The market prices it at 64.1%. That five-point gap is where the value lives, and it is worth a small unit on the Cardinals to exploit it.

St. Louis Cardinals vs Detroit Tigers Key Insights

  • Dustin May's 13.50 ERA and 10 hits allowed across four innings signals structural command problems. A short outing of three to four innings is the base case, not the pessimistic one.
  • Comerica Park carries a 0.97 runs factor and a 0.92 home run factor, reinforcing a low-scoring environment that supports the Under even if May exits early and the Cardinals bullpen inherits the game.
  • Our model projects 7.3 combined runs against a 7.5 market line, a directional Under signal that aligns with Flaherty's track record against this Cardinals roster and Comerica's suppressive park factor.
  • McGonigle's .945 OPS versus right-handed pitching and May's documented platoon vulnerability create a structural matchup edge for the Tigers shortstop independent of overall game flow.
  • Flaherty's 2024 gem against St. Louis (6.2 IP, 0 ER, 14 K) sets a meaningful ceiling, but his 2026 strikeout rate of 2 K in 4.1 innings shows he is currently pitching to contact rather than missing bats, making the Under 5.5 K prop well-supported.
  • The Cardinals' 4.13 bullpen ERA limits blowout risk even if May exits by the fourth inning, supporting the Cardinals +1.5 run line and keeping the total suppressed in the later innings.

St. Louis Cardinals vs Detroit Tigers Betting Picks

Picks made April 04, 2026 at 04:28 AM ET. Odds shown reflect current market prices.

Cardinals +1.5 run line (-172, LOW confidence)
Cardinals +1.5 run line (-172, LOW confidence): The model projects a 4.1-3.2 final, a 0.9-run margin. The Cardinals cover +1.5 in most modeled outcomes by either winning outright (41.1% model win probability) or keeping Detroit to a single run. The -172 price is steep and confidence is low, but structurally the narrow projected margin makes this the logical underdog run line in the context of the slate.
Cardinals moneyline (+124, LOW confidence, contrarian)
Cardinals moneyline (+124, LOW confidence, contrarian): The market prices Detroit at -179, implying 64.1% win probability. Our model says 58.9%. That five-point gap is a market overreaction to one May disaster. Flaherty's own 2026 command (4 walks in 4.1 IP) narrows Detroit's true edge below what the price reflects. Cardinals ML at +124 targets that inefficiency. Keep this a small unit given the uncertainty around May's short-term durability.
Kevin McGonigle Over 0.5 hits (-233, HIGH confidence)
Kevin McGonigle Over 0.5 hits (-233, HIGH confidence): The highest-confidence play on this card. McGonigle is hitting .346 this season with a .945 OPS against right-handed pitching. No career matchup data exists against May, but the season profile is clear: a left-handed bat running a .346 average faces a pitcher with documented platoon vulnerability and fastball command problems. At -233 the market acknowledges the edge. The price is steep, but the structural case is as clean as it gets.
Colt Keith Over 1.5 total bases (+126, MEDIUM confidence)
Colt Keith Over 1.5 total bases (+126, MEDIUM confidence): Keith is slashing .364/.417/.545 with a 1.037 OPS over the last seven days. His .545 slugging percentage and extra-base hit profile (multiple doubles already this season) give him a strong path to 2 or more total bases. May's platoon splits benefit left-handed bats like Keith, and at +126 the market is pricing this as roughly a coin flip. Given Keith's current form and the matchup context, that line undervalues this bat.
Masyn Winn Under 0.5 hits (+142, MEDIUM confidence)
Masyn Winn Under 0.5 hits (+142, MEDIUM confidence): Winn is slashing .179/.233/.250 with a .348 OPS against right-handed pitching, the lowest mark among regular Cardinals starters. His career record against Flaherty is 0-for-2 (2 PA, .000 average and .000 OPS), a small sample but directionally consistent with a weak season line. Positive odds on a batter with a .179 average facing a pitcher he has never hit in limited career looks is a legitimate value position.
Dustin May Under 4.5 strikeouts (-112, MEDIUM confidence)
Dustin May Under 4.5 strikeouts (-112, MEDIUM confidence): May's last three starts produced 3, 1, and 5 strikeouts respectively, averaging 3.0 per outing. His 2026 debut managed just 3 Ks across four innings. One analyst noted: "Considering those command issues, May should rely more on his off-speed stuff." Relying on off-speed pitches against a contact-heavy lineup historically suppresses strikeout rates. A projected short leash of three to four innings limits his plate appearances further. At -112, the market sees this as near 50/50. It should not be.
Jack Flaherty Under 5.5 strikeouts (-120, MEDIUM confidence)
Jack Flaherty Under 5.5 strikeouts (-120, MEDIUM confidence): Flaherty's 2026 K totals are strikingly low: 2 strikeouts in 4.1 innings in his only start this season. His last three outings averaged 3.3 Ks. He is walking batters (4 BBs in 4.1 IP) and pitching to contact rather than generating swing-and-miss. His 14-K performance against this Cardinals lineup in 2024 was a different Flaherty. The current version earns outs through contact, and Under 5.5 at -120 reflects that reality.
SGP (4 legs)
SGP (4 legs): Cardinals +1.5, Under 7.5, Flaherty Under 5.5 strikeouts, McGonigle Over 0.5 hits: The thesis is interconnected. A low-scoring environment keeps the game close, supporting both the Cardinals staying within a run and a half and the total staying under 7.5. Flaherty pitching to contact in a tight game aligns with modest strikeout totals. McGonigle recording a hit against May is the high-confidence anchor leg that survives in any scoring environment. Four legs built around a coherent, park-driven, matchup-driven narrative.
Analysis insight — no specific bet associated
YRFI (-103)
YRFI (-103): Both starters carry elevated first-inning risk. May's fastball command issues and Detroit's left-handed lineup against his platoon splits favor early Tigers baserunners. Flaherty's first-inning profile has been elevated this season as well. Detroit has scored in the first inning in roughly 3 of 7 games (42.9%) and St. Louis in about 2 of 7 (28.6%), combining to an estimated 59% YRFI probability. The market prices YRFI at roughly 50% after vig adjustment. At -103, you are paying almost nothing to capture that edge.

Key Players

Batting AverageSTL
Victor Scott II
.333Batting Average
CF
Home RunsSTL
Nolan Gorman
2Home Runs
2B
Runs Batted InSTL
Nolan Gorman
6Runs Batted In
2B
Earned Run AverageSTL
Matthew Liberatore
1.64Earned Run Average
SP
WinsSTL
Andre Pallante
1Wins
SP
StrikeoutsSTL
Michael McGreevy
9Strikeouts
SP
Batting AverageDET
Colt Keith
.364Batting Average
2B
Home RunsDET
Dillon Dingler
2Home Runs
C
Runs Batted InDET
Dillon Dingler
7Runs Batted In
C
Earned Run AverageDET
Tarik Skubal
0.69Earned Run Average
SP
WinsDET
Tarik Skubal
1Wins
SP
StrikeoutsDET
Framber Valdez
10Strikeouts
SP

Recent Form

St. Louis Cardinals
L11-7Tampa Bay Rays
L4-2New York Mets
W3-0New York Mets
L4-0Detroit Tigers
Detroit Tigers
L3-0San Diego Padres
L9-6Arizona Diamondbacks
L7-5Arizona Diamondbacks
L1-0Arizona Diamondbacks
W4-0St. Louis Cardinals

St. Louis Cardinals vs Detroit Tigers Summary

Our model projects a 4.1-3.2 final and 7.3 combined runs. The Under 7.5 is the anchor pick here, and it has multiple pillars. Comerica Park suppresses scoring structurally. The Cardinals bullpen at 4.13 ERA limits late-inning run surges even after May exits. Flaherty's 2024 ceiling against this St. Louis roster, 6.2 shutout innings and 14 strikeouts, is a real reference point for what tonight could look like if he rediscovers that form. I would project closer to a 4-3 final than anything approaching six or seven total runs, consistent with both the model and the environment.

The best individual play on this card is McGonigle Over 0.5 hits. Left-handed bat, .346 average, documented platoon edge against a pitcher with fastball command problems. The structural case is clean. For bettors looking for secondary exposure, the Cardinals ML at +124 is the contrarian angle. The market has overpriced Detroit's edge based on one May outing. St. Louis is 4-3, handles close games well (2-0 in extras), and carries a capable bullpen. Our model gives the Tigers only 58.9% to win. The market prices it at 64.1%. Those five points represent real inefficiency, and a small unit on the Cardinals captures it without overcommitting to May's durability.

The caveat is worth stating plainly. May has six days of rest and could settle into a rhythm after a rocky opener. If his fastball finds the strike zone early, the total climbs and the Cardinals run line becomes harder to cover. Flaherty's 2024 performance against this lineup is a genuine data point in Detroit's favor, and if he finds that version of himself, this game looks more dominant than the model suggests. The Under, the run line, and the McGonigle hit prop all survive a range of outcomes. The Cardinals moneyline carries more variance and should be sized accordingly.

Head-to-Head History

Season SeriesDET leads series 1-0
DateMatchupResult
Apr 03, 2026STL @ DETDETDET 4-0

Compare odds for STL @ DET

Frequently Asked Questions

MLBGame PreviewsSt. Louis Cardinals at Detroit Tigers