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MLBGame PreviewsMinnesota Twins at Chicago White Sox
Minnesota TwinsMinnesota Twins
@
Rate Field
Chicago White SoxChicago White Sox

Match Predictor

Pre-match Prediction
Minnesota Twins
@
Chicago White Sox
Minnesota Twins 50%Chicago White Sox 50%
Market LinesRun Line: Chicago White Sox -1Total: O/U 8
Model: Under 8
Model projects 7.8 total runs vs 8 line

Minnesota Twins

0022446688101012121414OVERUNDERO/U 8Runs ScoredRuns Allowed
All Over 8
51%
27/53
MLB: 48%
Starter
50%
1/2
vs CHW
Avg Total
9.3
MLB: 8.9
Game Starter (2) Last Starter vs CHW vs CHW (0)
Zebby Matthews #52 · RHP · Age 26
1.38
ERA (2026)
7.6
K/9 (2026)
2
Starts (2026)
6.5
Avg Total (2026)
Last 3:
L HOU (May 19): 6.0IP, 2ER, 6K
W MIA (May 14): 7.0IP, 0ER, 5K
W @TEX (Sep 23): 7.0IP, 1ER, 6K
vs CHW: ND (Aug 22 2025): 4.2 IP, 4 ER, 4 K
Bullpen (2026 Season)Poor
ERA: 4.90MLB Avg: 3.958 relievers
Recent: L 1-2W 4-1W 8-6W 4-2W 6-5
Lineup vs Zebby Matthews (Career)
BatterPosPAAVGOPSHR
Colson MontgomerySS6.3331.3331
Andrew BenintendiDH5.0000.2000
Edgar QueroC5.4001.4001
Chase Meidroth2B4.0000.0000
Miguel Vargas3B3.0000.3330
8 batters with no matchup history

Chicago White Sox

0022446688101012121414OVERUNDERO/U 8Runs ScoredRuns Allowed
All Over 8
58%
30/52
MLB: 48%
Starter
38%
3/8
vs MIN
Avg Total
9.4
MLB: 8.9
Game Starter (8) Last Starter vs MIN vs MIN (0)
Anthony Kay #18 · LHP · Age 31
4.27
ERA (2026)
6.6
K/9 (2026)
8
Starts (2026)
9.5
Avg Total (2026)
Last 3:
ND @SEA (May 19): 5.1IP, 1ER, 5K
W KC (May 14): 6.0IP, 2ER, 4K
W SEA (May 09): 5.0IP, 0ER, 5K
Bullpen (2026 Season)Average
ERA: 4.12MLB Avg: 3.9511 relievers
Workload Alert: Allowed 10 runs on 2026-05-23 vs SF. Bullpen arms likely still recovering.
Recent: W 2-1L 4-5W 9-4L 3-10L 5-8
Lineup vs Anthony Kay (Career)
BatterPosPAAVGOPSHR
Josh BellDH1.0001.0000
Victor CaratiniC1.0001.0000
11 batters with no matchup history
Our Top PicksLive Odds
Top PickMinnesota Twins ML (-105)
The market prices this as a coin flip, but the coin is not fair.
PickMinnesota Twins -1.0 (+106)
Plus money on the Twins to win by two or more is where the best value sits in this game.
PickUnder 8.5 (-123)
The directional lean here is Under, driven by Matthews' contact-suppression approach.

Minnesota Twins vs Chicago White Sox Game Preview

Zebby Matthews is the entire story here, and every other angle orbits around him. The 26-year-old right-hander walked into 2026 on fumes. Across 117 combined innings in 2024 and 2025, he posted a 6.12 ERA with pedestrian command. Now he has issued one walk in 13 innings. One. His 0.69 BB/9 in 2026 is not a rounding error. His last three starts include a zero-walk, six-inning effort against Houston and a seven-inning shutout against Miami. The 1.38 ERA is the number the market does not appear to believe, and at -105, the Minnesota Twins are priced as though it does not matter. It does.

The pitcher opposing Matthews offers a sharper illustration of what ordinary command looks like. Anthony Kay takes the mound for the Chicago White Sox with a 4.27 ERA and 22 walks in 46.1 innings, a 4.28 BB/9 that creates traffic, inflates pitch counts, and invites trouble even when the damage does not show up immediately. Kay is a lefty, which gives Chicago a natural platoon edge against a Minnesota lineup that is 9-11 against left-handed pitching this season. That edge is real. So is his walk problem. In tonight's MLB action, command is the differentiator, and these two starters are not close on that metric.

Minnesota arrives on a four-game win streak, including three wins on the road at Fenway Park. Their 11-13 away record is unimpressive on paper, but the recent momentum is genuine. Chicago returns home after being outscored 18-8 in two games in San Francisco, dropping both. The White Sox are 26-26 overall, technically at .500, but their season run differential sits at -17 and they looked rough in that final Bay Area series. Rate Field's 1.08 HR park factor keeps the ceiling alive for a big swing, but this is not an offense positioned to solve an elite-command pitcher right now.

One development worth noting: the White Sox called up infielder/outfielder Rikuu Nishida from Triple-A Charlotte on the day of this game. In 33 Charlotte games, Nishida posted a .454 OBP with 9 stolen bases and brings legitimate speed and on-base ability. As White Sox Director of Player Development Paul Janish said: "He's one of the best baseball players that we have in our organization. He is contagious in the best way. The players around him get better." His call-up adds lineup flexibility, but he carries no career data against Matthews. On the BvP front, Andrew Benintendi is 0-for-5 with a 0.200 OPS lifetime against Matthews, and Chase Meidroth is 0-for-4 with a 0.000 OPS. The contact-suppression profile works even when the strikeouts do not pile up, and this lineup has demonstrated it against this specific pitcher before.

Minnesota Twins vs Chicago White Sox Key Insights

  • Matthews issued one walk across 13 innings in 2026 (0.69 BB/9), compared to Kay's 4.28 BB/9. The command gap between these two starters is the sharpest, most measurable edge anywhere in this game.
  • Benintendi is 0-for-5 with a 0.200 OPS lifetime against Matthews; Meidroth is 0-for-4 with a 0.000 OPS. Both are projected middle-of-order contributors against this specific pitcher, and neither has recorded a hit against him.
  • The White Sox were outscored 18-8 in their final two games in San Francisco, arriving home on a two-game losing streak. Their season run differential of -17 is the underlying number that puts the recent slide in context.
  • Byron Buxton carries a 1.005 OPS versus right-handed pitching in 2026, with 16 home runs and a .578 SLG. Kay has allowed 6 HR in 46.1 innings (1.17 HR/9), and Rate Field adds a 1.08 HR park factor. That math is dangerous for any righty giving up fly balls.
  • Matthews' two prior appearances against Chicago in 2025 produced 5 K in 6 IP and 4 K in 4.2 IP, averaging 4.5 Ks per outing against this lineup. The CHW matchup history is the specific evidence pulling his strikeout expectation below the 5.5 line today.
  • The contrarian case for Chicago is legitimate: Kay's LHP advantage versus a 9-11 Twins lineup against southpaws, plus Matthews' 6.12 ERA across 117 career innings before this season, gives the White Sox an argument. The actual 2026 command data (one walk, not a projection) is why that case falls short, but bettors should size accordingly.

Minnesota Twins vs Chicago White Sox Betting Picks

Picks made May 25, 2026 at 04:10 AM ET. Odds shown reflect current market prices.

Minnesota Twins -1.0 (+106)
Minnesota Twins -1.0 (+106): Plus money on the Twins to win by two or more is where the best value sits in this game. Matthews' command-first profile limits traffic and soft-contact damage. Kay's walk issues make a multi-run Minnesota advantage more likely than the line suggests. A clean Matthews start through five or six innings turns this into a legitimate run-line cover, and the +106 price makes the math work.
Under 8.5 (-123)
Under 8.5 (-123): The directional lean here is Under, driven by Matthews' contact-suppression approach. He is not generating elite strikeout numbers, but the one-walk efficiency keeps pitch counts low and innings clean. Kay's walk rate is the counterargument since base runners mean more chances for runs, but the 8.5 line absorbs that risk. Thin edge, low confidence, but directionally consistent with the pitching matchup.
Zebby Matthews Under 5.5 Strikeouts (-149)
Zebby Matthews Under 5.5 Strikeouts (-149): Matthews averages 7.62 K/9 in 2026, but his two outings against this Chicago lineup in 2025 produced 5 K in 6 IP and 4 K in 4.2 IP, an average of 4.5 Ks per start. This is a lineup that has seen him, and the BvP history suggests they make contact rather than swing and miss. His low walk rate points to a contact-suppression approach more than a swing-and-miss one. The matchup history is the specific evidence backing the Under here.
Andrew Benintendi Under 0.5 Hits (+118)
Andrew Benintendi Under 0.5 Hits (+118): Benintendi is 0-for-5 with a 0.200 OPS lifetime against Matthews, going hitless across all five career plate appearances. His 2026 season slash of .232/.279/.371 is below average, and a 0.350 OPS over the last seven days confirms a cold stretch. Facing an improved command pitcher with direct BvP evidence of total futility, the hitless-game probability at +118 offers genuine value.
Chase Meidroth Under 0.5 Hits (+148)
Chase Meidroth Under 0.5 Hits (+148): The BvP case here is as clean as it gets. Meidroth is 0-for-4 with a 0.000 OPS against Matthews, generating zero contact value across four plate appearances in 2025. His 2026 OPS versus right-handed pitching is just 0.612, one of the weaker RHP splits in the Chicago lineup. At +148, the market underestimates what the direct matchup history is telling us. This is one of the better-supported player prop leans on the board today.
Byron Buxton Anytime Home Run (+300)
Byron Buxton Anytime Home Run (+300): Buxton is the most dangerous bat in this game. His 1.005 OPS versus right-handed pitching in 2026, 16 home runs in 204 PA, and .578 SLG are legitimately elite power numbers. Kay has surrendered 6 HR in 46.1 innings (1.17 HR/9), and Rate Field's 1.08 HR park factor adds a consistent boost to anything hit in the air. Even in an under-leaning game, Buxton's ceiling makes +300 an attractive anytime HR price. Low-floor bet by nature, but the matchup math points in his direction.
Munetaka Murakami Over 1.5 Total Bases (+112)
Munetaka Murakami Over 1.5 Total Bases (+112): Murakami leads the White Sox with 17 HR, a .530 SLG, and a .934 OPS versus right-handed pitching this season. He is the most dangerous power bat in the Chicago lineup facing a righty. Kay's 4.28 BB/9 drives up pitch counts and increases the probability that Murakami sees a hittable pitch in a leverage count. Rate Field's 1.08 HR factor amplifies his extra-base ceiling further. Over 1.5 total bases at +112 is a fair price for a hitter with this power profile against this pitcher.
YRFI (-111)
YRFI (-111): This is a low-confidence speculative lean, not a conviction play. First-inning split data was unavailable for both starters, so the reasoning relies on broader 2026 context. Kay's 4.28 BB/9 creates genuine first-inning vulnerability against a Twins lineup scoring 4.7 runs per game on a four-game win streak. The YRFI at -111 is marginally less expensive than the NRFI side, and Minnesota's offensive momentum is the supporting argument. Treat this as a small-unit add, not an anchor bet.
Same-Game Parlay (4 Legs)
Same-Game Parlay (4 Legs): Twins -1.0 (+106), Under 8.5 (-123), Matthews Under 5.5 Strikeouts (-149), Murakami Over 1.5 Total Bases (+112). The thesis: Minnesota wins by two or more in a low-scoring game where Matthews is efficient but not dominant, Murakami delivers an extra-base hit against Kay, and the total stays beneath 8.5. A Twins run-line cover in an under game is the specific scenario where all four legs connect cleanly. The legs are internally consistent: pitching suppresses overall offense, Murakami provides the one exception that benefits Chicago without blowing up the total.
Analysis insight — no specific bet associated

Key Players

Batting AverageMIN
Austin Martin
.297Batting Average
LF
Home RunsMIN
Byron Buxton
16Home Runs
CF
Runs Batted InMIN
Josh Bell
30Runs Batted In
DH
Earned Run AverageMIN
Joe Ryan
3.02Earned Run Average
SP
WinsMIN
Bailey Ober
6Wins
SP
StrikeoutsMIN
Joe Ryan
61Strikeouts
SP
Batting AverageCHW
Chase Meidroth
.261Batting Average
2B
Home RunsCHW
Munetaka Murakami
17Home Runs
1B
Runs Batted InCHW
Munetaka Murakami
36Runs Batted In
1B
Earned Run AverageCHW
Davis Martin
2.04Earned Run Average
SP
WinsCHW
Davis Martin
7Wins
SP
StrikeoutsCHW
Davis Martin
66Strikeouts
SP

Recent Form

Minnesota Twins
L2-1Houston Astros
W4-1Houston Astros
W8-6Boston Red Sox
W4-2Boston Red Sox
W6-5Boston Red Sox
Chicago White Sox
W2-1Seattle Mariners
L5-4Seattle Mariners
W9-4San Francisco Giants
L10-3San Francisco Giants
L8-5San Francisco Giants

Minnesota Twins vs Chicago White Sox Summary

The case for the Minnesota Twins comes back to one pitcher and one number: one walk in 13 innings. Matthews' 2026 command transformation is the most specific, documented edge in this game. The market prices this matchup as a coin flip at -105 on both sides, and that gap between perception and observed data is where the value lives. Minnesota takes the moneyline at -105 and the -1.0 run line at +106, the latter being the plus-money extension of the same argument. If Matthews is sharp through five innings, the Twins cover by two. If his walk rate holds against a White Sox lineup that has already demonstrated it struggles to get base hits against him (Benintendi 0-for-5, Meidroth 0-for-4), Chicago will not put enough runs on the board to make this competitive. The Under 8.5 at -123 is the natural companion to that scenario: a clean Matthews start suppresses the run environment on one side, and the Twins do not need to score six or seven to win this game.

The best supporting props make the card more interesting. Benintendi and Meidroth hit unders are the most directly supported plays on the board, backed by BvP evidence rather than general tendency. Buxton at +300 for an anytime HR is the speculative power play: Kay surrenders more than a homer per nine, Rate Field amplifies the risk by 8%, and Buxton's 1.005 vR OPS makes him the most likely single-swing game-changer for Minnesota. On Chicago's side, Murakami at +112 for over 1.5 total bases is a reasonable hold given his 17 HR and .934 vR OPS against Kay's command issues. The park will not punish extra-base contact.

One caveat worth stating plainly: Matthews has 13 innings of 2026 data. That is a real sample-size concern and the single strongest argument for the contrarian White Sox position. His combined 6.12 ERA across 117 innings in 2024 and 2025 is the counterevidence, and two rough outings against this same Chicago lineup in 2025 (4 ER in 10.2 IP combined) are why regression risk remains on the table. Colson Montgomery owns a 1.333 OPS against him in 6 career PA, and Edgar Quero has a 1.400 OPS in 5 PA. If Matthews walks two batters early, the regression narrative writes itself fast. Bet with appropriate sizing and understand this is a lean on observed command, not a guarantee. For the full slate, see our MLB picks today, NRFI picks, and player props.

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MLBGame PreviewsMinnesota Twins at Chicago White Sox