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The Minnesota Timberwolves have won five straight, holding opponents to just 102.0 points per game in that stretch. Their defensive rating of 103.8 is No. 1 in the league. But Anthony Edwards is out after a right knee arthroscopic procedure, and that matters for one specific reason: his 36.6% usage rate and 33.3 points per game are the engine behind Minnesota's blowout capacity. Without him tonight, the Wolves are still the better team by a wide margin, but they are not the same game-killing machine they were two weeks ago.
Here's where the matchup gets interesting. Ayo Dosunmu is playing his first game against his former team tonight. Illinois alum, Chicago native, back against the Bulls. The revenge angle is real, and the numbers support it. He drives 14.6 times per game at 52.9% from those drives, with a 62.4 TS%, the highest of any Minnesota starter this season. Chicago ranks 30th in paint defense with a 124.2 DEFRTG. That is the worst interior defense in the NBA. As one beat writer put it, Dosunmu and Terrence Shannon Jr. should "have a field day attacking the cup against the 30th ranked team in points given up in the paint."
One more layer. Chicago pushes pace faster than anyone in the league at 103.83 (No. 1). Minnesota sits sixth at 101.08. That gap means more possessions than a typical Wolves game, which cuts against a low total in theory. In practice, translating those extra possessions into actual points against a 103.8 DRTG defense, while running on empty in the second game of a back-to-back, is a completely different problem.
Picks made November 14, 2026 at 06:29 AM ET. Odds shown reflect current market prices.
The two picks I keep returning to are Under 233.5 at +110 and Giddey Over 8.5 assists at -128. The under is a value bet where plus-money reflects a scenario that two compromised offenses and the NBA's best defense strongly support. Giddey's facilitation volume holds even in a blowout because the Bulls keep running offense regardless of the score, and Minnesota's defense routes more possessions through passing lanes than isolation attempts. If you want to build from the matchup up rather than the top-line odds down, those two legs anchor the night. The SGP threading all four correlated legs together is the high-upside play for the ticket hunters. As always, results are never guaranteed, and bet only within your limits.
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Bulls vs Timberwolves predictions: Edwards out, back-to-back Bulls face NBA's No. 1 defense. Best bet: Under 233.5 at +110 with both offenses compromised.