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IND
Game Preview
The Indianapolis Colts visit the Los Angeles Rams at SoFi Stadium on Sept. 28. Kickoff is 1:00 PM ET. Los Angeles is the favorite, but the market still respects Indy’s 3-0 start.
Daniel Jones has rebuilt his stock with efficient play, and he gets a defense that has leaked chunk throws. On the other side, the Rams still create explosives through the air. That is their identity, with or without a full offensive line.
Health will shape this game. The Colts are thin at corner. Charvarius Ward is out and Kenny Moore II is doubtful. The Rams list several linemen as questionable, and Davante Adams is also questionable. Late news could swing matchups and pace.
In short, expect a clean Colts pocket against a middling Rams rush, and a Rams pass game that tests a shorthanded secondary. If the Rams’ line holds up, their deep shots become the X-factor.
Current Season Form
LAR
AwayIND
HomeHead-to-Head Summary
Past Results
| Date | Opponent | Result | ATS | O/U |
|---|---|---|---|---|
| 2025-09-21 | @ PHI | L 26-33 | L 3.5 | o45.5 |
| 2025-09-14 | @ TEN | W 33-19 | W +-5.5 | o41.5 |
| 2025-09-07 | vs HOU | W 14-9 | W +3.5 | u43.5 |
| 2025-01-19 | @ PHI | L 22-28 | L 7.0 | o43.5 |
| 2025-01-13 | vs MIN | W 27-9 | W +-2.5 | u47.5 |
| 2025-01-05 | vs SEA | L 25-30 | L -7.5 | o38.5 |
| 2024-12-28 | vs ARI | W 13-9 | W +6.5 | u48.0 |
| 2024-12-22 | @ NYJ | W 19-9 | W +-3.0 | u47.0 |
| 2024-12-12 | @ SF | W 12-6 | W +3.0 | u48.5 |
| 2024-12-08 | vs BUF | W 44-42 | L -3.5 | o49.5 |
Key Insights
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Indy can throw on this defense. The Colts post an 8.9% explosive pass rate (83rd percentile; sample 90). The Rams allow explosive passes at 8.4% (23rd; sample 166).
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Rams bring top-end explosive ability. Los Angeles owns a 12.4% explosive pass rate (100th; sample 97). That pressure targets a Colts secondary missing pieces.
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Protection favors Indy. The Colts allow sacks on only 2.2% of dropbacks (94th; sample 90). The Rams’ sack-rate generated sits at 7.1% (61st; sample 169).
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Colts run defense has sprung leaks. Indy has allowed explosive runs on 10.2% of rushes (sample 59, small sample). That fits Kyren Williams’ workload.
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Situational football splits. Indy’s red-zone TD rate is 35.3% (12th percentile; sample 17, small sample), while the Rams’ defense allows TDs on only 41.2% in the red zone (88th; sample 17).
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Style contrast. The Rams line up under center 76.4% of the time (100th; sample 229), while the Colts favor shotgun at 55.9% (77th; sample 236). That affects play-action depth and pass rush angles.
Betting Insights
Anchor spread: Rams -4.0 at +102. Not a -3 or -3.5, so expect swing risk around late field goals.
Anchor total: 48.5 with Over -128 and Under -104. Juice leans Over, but injuries could whipsaw pace.
Moneyline shape: Rams -182 vs Colts +158. Price implies Los Angeles wins about two-thirds of the time, not a lock.
Daniel Jones over 215.5 passing yards (-119): Rams rank 23rd percentile in explosive-pass prevention, which helps modest yardage overs.
Michael Pittman Jr. over 51.5 receiving yards (-118): Fits the same matchup. Safe role, fair price.
Kyren Williams over 70.5 rushing yards (-122): Colts have allowed a high explosive-run rate (small sample). Juice is heavier, size accordingly.
Puka Nacua over 92.5 receiving yards (-119): Colts are thin at CB. If Davante Adams sits, Nacua’s target share can spike. If Adams plays, volume is still strong, but variance rises.
Josh Downs over 37.5 receiving yards (-119): Matchup friendly, but he is Questionable, so expect volatility.
Final Summary
This looks like a pass-lean game for the Colts and a shot-play game for the Rams. Indy protects well, which keeps Jones on schedule. The Rams, when healthy up front, can hit explosives against a short-handed secondary.
The betting market sets a near key-number favorite at Rams -4.0 and a total of 48.5. That says points, but the juice and the injury list demand caution. Track the Rams’ offensive line and Davante Adams before kickoff.
If Adams is limited, expect more Puka Nacua and Kyren Williams. If the Colts get one of their questionable WRs cleared, Jones has enough to press the Rams’ downfield weakness.
Price sensitivity matters here. Several props sit between -118 and -128. That is real juice. Scale bet size and expect variance in a game that can swing on two or three explosive plays.
Statistical Battle Boards
OffenseDefense| Statistic | Offense | Rank | Defense | Rank | Advantage |
|---|---|---|---|---|---|
| Total Points | 103 | #2 | 61 | #19 | |
| Total Points Per Game | 34.3 | #2 | 20.3 | #14 | |
| Total Touchdowns | 9 | #7 | 6 | #14 | |
| Passing Touchdowns | 3 | #28 | 4 | #10 | |
| Rushing Touchdowns | 6 | #4 | 1 | #3 | |
| Other Touchdowns | 0 | #12 | 1 | #24 | |
| Total Kicking Points | 43 | #1 | 25 | #13 | |
| Total Two Point Conversions | 0 | #30 | 0 | #25 | |
| Kick Extra Points | 10 | #5 | 4 | #26 | |
OffenseDefense| Statistic | Offense | Rank | Defense | Rank | Advantage |
|---|---|---|---|---|---|
| Net Passing Yards | 796 | #4 | 496 | #27 | |
| Net Passing Yards Per Game | 265 | #4 | 165 | #27 | |
| Passer Rating | 112 | #3 | 92.2 | #17 | |
| Passing Attempts | 88 | #25 | 92 | #14 | |
| Completions | 63 | #13 | 59 | #23 | |
| Completion Percentage | 71.6 | #3 | 64.1 | #13 | |
| Passing 1st downs | 40 | #4 | 26 | #7 | |
| Passing 1st Down % | 53.3 | #21 | 47.3 | #3 | |
| Longest Pass | 44 | #23 | 38 | #26 | |
| Passing Fumbles Lost | 0 | #20 | 3 | #2 | |
| Receiving Targets | 87 | #23 | 88 | #20 | |
| Receptions | 63 | #13 | 59 | #11 | |
| Receiving Yards After Catch | 363 | #4 | 216 | #3 | |
| YAC Average | 5.8 | #4 | 3.7 | #3 | |
OffenseDefense| Statistic | Offense | Rank | Defense | Rank | Advantage |
|---|---|---|---|---|---|
| Rushing Yards | 460 | #3 | 309 | #13 | |
| Rushing Yards Per Game | 153 | #3 | 103 | #20 | |
| Rushing Attempts | 100 | #2 | 80 | #17 | |
| Yards Per Rush Attempt | 4.6 | #11 | 3.9 | #22 | |
| Rushing 1st downs | 26 | #3 | 23 | #24 | |
| 20+ Yard Rushing Plays | 2 | #8 | 0 | #28 | |
| Long Rushing | 68 | #3 | 18 | #29 | |
| Rushing Fumbles | 2 | #8 | 0 | #28 | |
| Rushing Fumbles Lost | 0 | #25 | 0 | #19 | |
Game Preview of Indianapolis Colts @ Los Angeles Rams. Week 4 of 2025 NFL Season
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