• Omarion Hampton has boosted the Chargers’ ground game, which ranks in the top 12% for explosive runs at 6.6%.

• The Chargers have struggled in the red zone, converting only 36.4% of trips into touchdowns.

• Washington’s receiving corps is battered, with McLaurin, Samuel, and Brown all questionable. That caps their explosive pass profile.

• The Commanders’ run defense ranked 30th last season and now faces a red-hot rookie in Hampton.

• The Chargers’ pass protection is shaky without both starting tackles, raising pressure risk against Washington’s front.

• Daniels’ return gives Washington mobility, but a knee brace and lack of WRs add volatility.

• Spread: Chargers -3.5 (-101). Market leans to LAC at home but juice suggests variance.

• Total: 48.5 (Over -110, Under -125). Odds shaded slightly to the under.

• Player Prop: Omarion Hampton over 66.5 rushing yards (-116). Faces a weak Washington run D.

• Player Prop: Jayden Daniels under 219.5 passing yards (-120). WR injuries limit deep ball chances.

• Player Prop: Keenan Allen over 55.5 receiving yards (-119). Washington secondary thin.

• Anytime TD: Omarion Hampton (-161). Lead back with red-zone role.

• Anytime TD: Jacory Croskey-Merritt (+150, if active). Washington RB carries scoring load.

This matchup is shaped by injuries. Washington gets Jayden Daniels back, but their top receivers are all questionable. Without Terry McLaurin and Deebo Samuel at full strength, Daniels may be forced to lean on short throws and his legs.

Los Angeles has its own issues. Their offensive line is down multiple starters, leaving Herbert exposed. The silver lining is Omarion Hampton, who adds an explosive rushing element. If he breaks a few runs, the Chargers can balance their offense.

Both defenses have been leaky. The Commanders give up big plays on the road, and the Chargers rank near the bottom in red-zone efficiency. That makes turnovers and red-zone stops even more critical.

The line favors the Chargers by just over a field goal, with a total around 48.5. Expect a competitive game where Daniels’ health and Hampton’s breakout play could swing the outcome.