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MLBGame PreviewsCincinnati Reds at Chicago Cubs
Cincinnati RedsCincinnati Reds
@
Wrigley Field
Chicago CubsChicago Cubs

Match Predictor

Pre-match Prediction
Cincinnati Reds
@
Chicago Cubs
Cincinnati Reds 36%Chicago Cubs 64%
Market LinesRun Line: Chicago Cubs -1Total: O/U 8.5
Model: Over 8.5
Model projects 8.6 total runs vs 8.5 line

Cincinnati Reds

0022446688101012121414OVERUNDERO/U 8.5Runs ScoredRuns Allowed
All Over 8.5
62%
23/37
MLB: 48%
Starter
57%
4/7
vs CHC
67%
2/3
Avg Total
8.9
MLB: 8.9
Game Starter (7) Last Starter vs CHC vs CHC (3)
Rhett Lowder #25 · RHP · Age 24
5.09
ERA (2026)
6.7
K/9 (2026)
7
Starts (2026)
9.9
Avg Total (2026)
Last 3:
L @PIT (May 02): 1.1IP, 8ER, 1K
ND DET (Apr 26): 5.0IP, 2ER, 7K
W @TB (Apr 20): 6.0IP, 1ER, 3K
vs CHC: ND (Sep 28 2024): 5.0 IP, 0 ER, 1 K
Bullpen (2026 Season)Good
ERA: 3.04MLB Avg: 3.959 relievers
Workload Alert: Allowed 17 runs on 2026-05-02 vs PIT. Bullpen arms likely still recovering.
Recent: L 7-17L 0-1L 4-5L 2-3L 6-7
Lineup vs Rhett Lowder (Career)
BatterPosPAAVGOPSHR
Alex Bregman3B3.0000.0000
Dansby SwansonSS3.0000.3330
Ian HappLF3.3330.6660
Michael Busch1B2.0000.0000
Miguel AmayaC2.5001.0000
Nico Hoerner2B2.0000.0000
Pete Crow-ArmstrongCF2.0000.0000
Seiya SuzukiRF2.10002.0000
5 batters with no matchup history

Chicago Cubs

0022446688101012121414OVERUNDERO/U 8.5Runs ScoredRuns Allowed
All Over 8.5
65%
24/37
MLB: 48%
Starter
57%
4/7
vs CIN
67%
2/3
Avg Total
9.6
MLB: 8.9
Game Starter (7) Last Starter vs CIN vs CIN (3)
Shota Imanaga #18 · LHP · Age 33
2.40
ERA (2026)
9.4
K/9 (2026)
7
Starts (2026)
7.7
Avg Total (2026)
Last 3:
W ARI (May 02): 7.0IP, 0ER, 5K
L @LAD (Apr 26): 5.1IP, 4ER, 6K
W PHI (Apr 21): 7.0IP, 1ER, 1K
vs CIN: W (Jun 09 2024): 6.2 IP, 2 ER, 7 K
Bullpen (2026 Season)Average
ERA: 4.13MLB Avg: 3.9510 relievers
Recent: W 2-0W 8-4W 5-4W 3-2W 7-6
Lineup vs Shota Imanaga (Career)
BatterPosPAAVGOPSHR
TJ FriedlCF9.2220.4440
Elly De La CruzSS8.0000.1250
Spencer SteerLF7.5001.5711
Matt McLain2B5.2001.0001
Jose TrevinoC4.0000.0000
Bryan Hayes3B4.0000.2500
JJ BledayLF3.0000.3330
Blake DunnLF2.0000.0000
5 batters with no matchup history
Our Top PicksLive Odds
Top PickChicago Cubs Moneyline (-208, MEDIUM)
The market implies a 67.6% Cubs win probability.
PickChicago Cubs -1.5 (-111, MEDIUM)
This is the best-value pick on the board.
PickUnder 8.5 Total Runs (-128, LOW)
The lean is specific, not reflexive.

Cincinnati Reds vs Chicago Cubs Game Preview

The MLB matchup closing this three-game series at Wrigley Field comes down to as clean a pitching imbalance as you will find on the Thursday slate. Chicago Cubs starter Shota Imanaga carries a 2.40 ERA, 43 strikeouts, and just 10 walks in 41.1 innings in 2026. That is elite command. Rhett Lowder, making the start for Cincinnati, brings the opposite: a 5.09 ERA, 14 walks in 35.1 innings, and a last outing where he lasted just 1.1 innings against Pittsburgh while surrendering 8 earned runs and 4 walks. These are not two pitchers on opposite ends of a normal performance gap. This is a structural mismatch, and it is the story of this game.

Chicago has already won the first two games of this series on walk-off hits and arrives at Game 3 riding an 8-game win streak with a 17-5 home record. As one beat writer confirmed: "In each of the Cubs' seven consecutive wins, their opponent has had a winning record going into the game." That tells you something about the level of competition this streak has absorbed. Michael Busch is the hottest individual bat in the lineup right now. A beat writer noted: "After hitting .194 in March and April, Busch is hitting .471 in 5 May games and .320 over his last 14 games." He has contributed walk-off and go-ahead hits in back-to-back games, and he now faces a right-hander who has issued 14 free passes in 35.1 innings this season.

The Cincinnati Reds arrive on a six-game losing streak, batting .219 as a team with a .689 OPS over 37 games. Their most dangerous bat, Elly Cruz, posts a 1.094 OPS against left-handed pitching overall this season. Against Imanaga specifically, that number disappears entirely. Cruz is 0-for-8 with a .125 OPS across 8 career plate appearances against Imanaga in 2024 and 2025. Two consecutive seasons of futility against one pitcher, despite being one of baseball's most feared lefty-killers in general. Cincinnati's 6-1 record against left-handed starters is a real organizational strength worth acknowledging, but it has not been tested against this specific pitcher, and the one Reds bat most likely to drive a rally is functionally neutralized in this matchup.

Weather at Wrigley adds another layer. The temperature sits around 52 degrees at game time with a northwest wind blowing in. A beat writer put it plainly: "Wrigley is cool, around 52 degrees with light northwest wind, so scoring must come from matchup quality and command." Wrigley's HR factor of 1.1 usually leans toward offense, but the NW wind flips that equation today. Runs need to come from base hits and contact quality, and only one starting pitcher on this field has demonstrated any ability to find the zone consistently in 2026.

Cincinnati Reds vs Chicago Cubs Key Insights

  • Imanaga's walk rate (10 BB in 41.1 IP) versus Lowder's command collapse (14 BB in 35.1 IP, 8 ER in 1.1 IP last start) is the most decisive pitching gap on today's board. One starter can locate consistently; the other just demonstrated he cannot stay in a game past the first inning.
  • Cruz has 10 home runs and a 1.094 OPS vs left-handed pitching this season, but he is 0-for-8 with a .125 OPS in 8 career PA against Imanaga across two seasons. That specific futility removes Cincinnati's primary power catalyst from the competitive equation today.
  • Spencer Steer is the one Reds bat with documented success against Imanaga: .500 average, 1.571 OPS, and a home run in 7 career PA, with results climbing from 1.167 OPS in 2024 to 1.750 OPS in 2025. He is Cincinnati's most credible offensive wildcard and worth monitoring throughout the game.
  • The Cubs' 17-5 home record and 8-game win streak reflect a team performing at the highest level in a controlled environment. A run differential of +45 over 37 games confirms consistent run creation and prevention, not a streak built on fluky close wins.
  • NW wind blowing into Wrigley at 52 degrees removes the fly-ball damage factor for both teams. Runs need to be manufactured through contact and walks, which favors the side with the better-commanded starter and the hotter lineup. Both of those belong to Chicago.
  • Cincinnati is 6-1 against left-handed starters this season, a genuine organizational strength. However, key Reds bats including Nathaniel Lowe, Sal Stewart, and Will Benson carry no career plate appearance history against Imanaga, meaning that 6-1 record has never faced this specific pitcher before today.

Cincinnati Reds vs Chicago Cubs Betting Picks

Picks made May 07, 2026 at 04:01 AM ET. Odds shown reflect current market prices.

Chicago Cubs -1.5 (-111, MEDIUM)
Chicago Cubs -1.5 (-111, MEDIUM): This is the best-value pick on the board. Getting Chicago at near-even money to win by two or more runs against a pitcher with a documented command collapse is efficient pricing. The analyst's expected game flow of 5-2 or 6-3 covers this line comfortably. If Lowder repeats his Pittsburgh pattern and exits before the fourth inning, Chicago's bullpen never faces meaningful pressure and the margin only grows. Cubs -1.5 at -111 is the anchor bet in this game.
Under 8.5 Total Runs (-128, LOW)
Under 8.5 Total Runs (-128, LOW): The lean is specific, not reflexive. NW wind blowing in at Wrigley suppresses fly-ball carry for both sides. Imanaga's elite control keeps Chicago's half of the run ledger clean. Even if Lowder exits early trailing 3-0 or 4-0, the game flow trends toward a 5-2 or 6-2 final rather than a double-digit blowout. Low confidence because no mathematical edge exists at this price relative to available market data, but the wind conditions and the pitching setup tip the needle toward the Under.
Shota Imanaga Over 5.5 Strikeouts (-141, MEDIUM)
Shota Imanaga Over 5.5 Strikeouts (-141, MEDIUM): Imanaga is running a 9.38 K/9 pace in 2026 with 43 strikeouts in 41.1 innings. Against Cincinnati specifically, he has logged 4, 7, and 7 strikeouts in his three career appearances versus this lineup, averaging 6 K per CIN start. The Reds are batting .219 as a team with a .689 OPS, creating significant swing-and-miss exposure across the lineup. The 1-strikeout outing against Philadelphia in April is the clear outlier in an otherwise dominant season. This is Imanaga at home against an offensively struggling team, in weather that suppresses contact quality even further.
Elly Cruz Under 0.5 Hits (+128, MEDIUM)
Elly Cruz Under 0.5 Hits (+128, MEDIUM): Eight career plate appearances against Imanaga. Zero hits. A .000 average in 2024 and a .200 OPS improvement to 2025, still leaving him hitless. Cruz posts a 1.094 OPS against left-handed pitching overall this year, which makes this specific futility against Imanaga more meaningful, not less. The market is paying you +128 to fade Cincinnati's best hitter against this exact pitcher. Two seasons of consistent BvP data say take it.
Spencer Steer Over 0.5 Hits (-172, MEDIUM)
Spencer Steer Over 0.5 Hits (-172, MEDIUM): Steer is the mirror image of Cruz in this matchup. Seven career PA against Imanaga, .500 batting average, 1.571 OPS, and a home run, with performance climbing from 1.167 OPS in 2024 to 1.750 OPS in 2025. His .940 OPS vs left-handed pitching this season confirms the BvP data is not a small-sample anomaly. He is also in strong current form with a .927 OPS over his last seven days. The juice at -172 reflects the reality of this matchup history.
Michael Busch Over 1.5 Total Bases (+116, MEDIUM)
Michael Busch Over 1.5 Total Bases (+116, MEDIUM): Busch is the hottest bat on the Cubs roster: .471 in May, 1.406 OPS over his last seven days, and walk-off and go-ahead contributions in back-to-back games. Lowder has allowed a 92.1 mph exit velocity against left-handed hitters and issued 14 walks in 35.1 innings this season. Busch bats left-handed. Even with wind blowing in, gap-to-gap contact still counts toward 2 total bases. Getting plus-money on the hottest hitter in the game against a right-hander with command problems is value worth taking.
Ian Happ Over 0.5 RBIs (+149, LOW)
Ian Happ Over 0.5 RBIs (+149, LOW): Happ posts a 0.994 OPS vs right-handed pitching this season and a scorching 1.319 OPS over his last seven days. He has 9 home runs and bats in the heart of a lineup averaging 5.4 runs per game. The low confidence reflects the Under lean on the total, which caps team scoring and reduces RBI opportunities. But at +149, the price compensates for that variance, and someone drives in runs when Chicago scores 5-6 runs. Happ is the most likely candidate.
Same-Game Parlay
Same-Game Parlay: Cubs -1.5 + Under 8.5 + Imanaga Over 5.5 K + Cruz Under 0.5 Hits: The four legs form a single clean narrative. Imanaga strikes out Cincinnati at his normal rate, Cruz goes hitless as he has in every previous meeting, the Reds fail to generate the offense needed to stay competitive, and Chicago wins by multiple runs while the total stays controlled. All four outcomes reinforce each other rather than pulling in different directions. Individual leg contract IDs: Cubs -1.5 (390414135), Under 8.5 (390414136), Imanaga strikeouts (390508838), Cruz hits (390508724). Treat this as a speculative add-on at reduced stake, not a primary bet.
Analysis insight — no specific bet associated
NRFI (-125, LOW)
NRFI (-125, LOW): No first-inning split data was available for either starter, so this lean is based on overall context rather than verified splits. Imanaga delivered a seven-inning shutout in his most recent start and carries the best walk rate on either roster in 2026. Cincinnati is on a six-game skid, batting .219 as a team, and has scored a combined 12 runs across three games in this series. Cool Wrigley conditions at 52 degrees suppress early power. At -125, this is near-coinflip pricing, but Imanaga's dominant recent form and CIN's offensive malaise justify the lean. Low confidence without verified first-inning splits.

Key Players

Batting AverageCIN
Elly De La Cruz
.267Batting Average
SS
Home RunsCIN
Elly De La Cruz
10Home Runs
SS
Runs Batted InCIN
Sal Stewart
29Runs Batted In
1B
Earned Run AverageCIN
Chase Burns
2.20Earned Run Average
SP
WinsCIN
Chase Burns
3Wins
SP
StrikeoutsCIN
Chase Burns
46Strikeouts
SP
Batting AverageCHC
Nico Hoerner
.290Batting Average
2B
Home RunsCHC
Ian Happ
9Home Runs
LF
Runs Batted InCHC
Nico Hoerner
27Runs Batted In
2B
Earned Run AverageCHC
Shota Imanaga
2.40Earned Run Average
SP
WinsCHC
Colin Rea
4Wins
SP
StrikeoutsCHC
Shota Imanaga
43Strikeouts
SP

Recent Form

Cincinnati Reds
L17-7Pittsburgh Pirates
L1-0Pittsburgh Pirates
L5-4Chicago Cubs
Chicago Cubs
W2-0Arizona Diamondbacks
W8-4Arizona Diamondbacks
W5-4Cincinnati Reds

Cincinnati Reds vs Chicago Cubs Summary

No score model is available for this game, but the directional case does not require one. Imanaga versus Lowder is one of the cleaner pitching setups on the board today, and every contextual factor reinforces the same side: Chicago at home, on a streak, with the hotter offense and cleaner starting pitcher, against a road team whose starter just allowed 8 runs in 1.1 innings. The analyst's expected game flow of 5-2 or 6-3 covers the Cubs -1.5 at -111 comfortably, making the run line the anchor bet. The Cubs moneyline at -208 is expensive but structurally sound. The Under 8.5 at -128 is a low-confidence lean supported by wind conditions and Imanaga's command rather than a hard mathematical edge. If you are building a card today, the run line is where the value lives.

The honest contrarian note: Cincinnati is 6-1 against left-handed starters, and that number is not a fluke. Spencer Steer carries a 1.571 OPS in 7 career PA against Imanaga with a home run in those appearances, making him the one Reds bat who could disrupt the dominant narrative. The analyst's secondary angle on Steer at +440 to go deep is a legitimate speculative play for bettors who want CIN exposure at a price that compensates for the structural disadvantage. But the primary case points one direction. The edge does not care what sport you are watching. Rest, context, price, same formula, different field. Today all three factors align with the Cubs closing out the sweep.

For the full slate, see our MLB picks today, NRFI picks, and player props.

Head-to-Head History

Season SeriesCHC lead series 3-0
DateMatchupResult
May 04, 2026CIN @ CHCCHCCHC 5-4
May 05, 2026CIN @ CHCCHCCHC 3-2
May 06, 2026CIN @ CHCCHCCHC 7-6

Compare odds for CIN @ CHC

Frequently Asked Questions

MLBGame PreviewsCincinnati Reds at Chicago Cubs