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MLBGame PreviewsCincinnati Reds at St. Louis Cardinals
Cincinnati RedsCincinnati Reds
@
Busch Stadium
St. Louis CardinalsSt. Louis Cardinals

Match Predictor

Pre-match Prediction
Cincinnati Reds
@
St. Louis Cardinals
Cincinnati Reds 47%St. Louis Cardinals 53%
Market LinesRun Line: St. Louis Cardinals -0.5Total: O/U 8.5
Model: Under 8.5
Model projects 8.0 total runs vs 8.5 line

Cincinnati Reds

0022446688101012121414OVERUNDERO/U 8.5Runs ScoredRuns Allowed
All Over 8.5
57%
58/102
MLB: 48%
Starter
67%
2/3
vs STL
67%
4/6
Avg Total
9.0
MLB: 8.9
Game Starter (3) Last Starter vs STL vs STL (6)
Hunter Greene #21 · RHP · Age 27
6.06
ERA (2026)
14.5
K/9 (2026)
3
Starts (2026)
10.7
Avg Total (2026)
Last 3:
W @COL (Jul 19): 6.0IP, 3ER, 7K
W CHC (Jul 10): 7.0IP, 0ER, 12K
L BAL (Jul 04): 3.1IP, 8ER, 7K
vs STL: L (Jun 30 2024): 4.2 IP, 1 ER, 6 K
Bullpen (2026 Season)Average
ERA: 4.28MLB Avg: 3.959 relievers
Workload Alert: Allowed 8 runs on 2026-07-20 vs SEA. Bullpen arms likely still recovering.
Recent: W 9-6L 0-8W 4-2W 5-3W 4-2
Lineup vs Hunter Greene (Career)
BatterPosPAAVGOPSHR
Lars NootbaarLF13.1110.4960
Alec Burleson1B11.2000.4730
Masyn WinnSS10.1000.2000
Jordan WalkerRF8.5711.3390
Jose FerminLF3.10002.0000
Nelson VelazquezLF2.0000.0000
Pedro PagesC2.10002.0000
6 batters with no matchup history

St. Louis Cardinals

0022446688101012121414OVERUNDERO/U 8.5Runs ScoredRuns Allowed
All Over 8.5
44%
45/103
MLB: 48%
Starter
58%
11/19
vs CIN
67%
4/6
Avg Total
8.9
MLB: 8.9
Game Starter (19) Last Starter vs CIN vs CIN (6)
Andre Pallante #53 · RHP · Age 28
4.02
ERA (2026)
6.4
K/9 (2026)
19
Starts (2026)
9.3
Avg Total (2026)
Last 3:
ND @ARI (Jul 19): 5.1IP, 3ER, 3K
L MIL (Jul 09): 5.0IP, 6ER, 2K
W @CHC (Jul 03): 5.2IP, 0ER, 2K
vs CIN: L (Aug 31 2025): 5.0 IP, 2 ER, 6 K
Bullpen (2026 Season)Average
ERA: 4.21MLB Avg: 3.958 relievers
Workload Alert: Allowed 10 runs on 2026-07-23 vs ARI. Bullpen arms likely still recovering.
Recent: L 2-3L 1-5W 1-0L 6-10L 2-4
Lineup vs Andre Pallante (Career)
BatterPosPAAVGOPSHR
Elly De La CruzSS26.2170.6120
TJ FriedlCF24.1740.3820
Spencer Steer1B21.2350.7931
Bryan Hayes3B15.2140.4810
Noelvi MarteRF14.3080.8950
Nathaniel LoweDH12.3641.3262
Tyler StephensonC9.2500.7080
Jose TrevinoC8.4291.3571
Dane MyersCF5.0000.0000
Eugenio SuarezDH5.2000.4000
Sal Stewart1B5.0000.4000
JJ BledayLF3.0000.0000
1 batters with no matchup history
Our Top PicksLive Odds
Top PickReds Moneyline (-109, MEDIUM)
The market prices this at 52.1% implied probability, essentially a coin flip.
PickReds -1.5 Run Line (+150, MEDIUM)
At plus money, this is the most attractive wager in the game if Greene delivers past five innings.
PickUnder 8.5 Runs (-112, LOW)
Busch Stadium, cool temperatures, showers near first pitch, and a Cardinals offense averaging 3.5 runs since the break all lean toward fewer combined runs.

Cincinnati Reds vs St. Louis Cardinals Game Preview

Hunter Greene has looked like a different pitcher over his last two starts. Seven innings, no runs, and 12 strikeouts against Chicago at home. Six innings, 3 runs, and 7 strikeouts at Colorado. That is 19 strikeouts across 13 innings with the stuff clearly intact, and tonight he faces a St. Louis Cardinals lineup that has historically failed to solve him. Masyn Winn is 1-for-10 (.100 AVG, 0.200 OPS) in 10 career plate appearances against Greene. Lars Nootbaar is 1-for-9 (.111 AVG, 0.496 OPS) in 13 PA. Alec Burleson is 2-for-10 (.200 AVG, 0.473 OPS) in 11 PA. One exception worth naming: Jordan Walker is 4-for-7 (.571 AVG, 1.339 OPS) in 8 career PA against Greene, all from 2023. Walker is the wild card. He has 0 home runs in 7 games since the All-Star break despite posting 100-plus MPH exit velocity repeatedly. That is a data point to keep in mind.

Andre Pallante counters for St. Louis, and the trend line is heading the wrong direction. His last three starts produced 3, 2, and 2 strikeouts. He gave up 6 earned runs in 5 innings against Milwaukee on July 9. His 2026 K/9 sits at 6.4, and his contact-yielding profile means trouble when the other team is locked in. The Cincinnati Reds won game 1 earlier today 4-2, and they come into game 2 with a specific edge waiting in the lineup. Nathaniel Lowe owns a .364 average, a 1.326 OPS, and 2 home runs in 12 career plate appearances against Pallante. His most recent 2026 appearances against this pitcher produced a 2.500 OPS in 2 PA. Small sample, consistent direction, and a .800 OPS over the last seven days makes him the clearest batter-pitcher edge in tonight's matchup.

The setting helps the pitchers. Busch Stadium plays slightly pitcher-friendly, with a runs factor of 0.98 and a home run factor of 0.95. Tonight's conditions tighten that further: showers near first pitch and a 69-degree evening limit fly-ball carry. That suppresses the entire offense, not just one side. Walker's 0 HR in 7 post-break games despite elite exit velocity is not a slump. The conditions are limiting ball travel. A cool, damp evening at a slightly pitcher-friendly park is the wrong environment to expect a high-scoring game, and it benefits a power pitcher like Greene who wins with strikeouts rather than passive weak contact.

The situational picture inside the Cardinals dugout is the real structural edge tonight. Riley O'Brien threw 63 pitches across three recent appearances. Matt Svanson threw 37 pitches on Thursday alone in a 10-6 loss to Arizona. Then St. Louis lost their scheduled off-day to a makeup game, meaning no rest buffer between Thursday and tonight. The bullpen arrives taxed, with second-tier arms likely absorbing late innings if this game stays close after five or six. Cincinnati had Thursday off. Every key reliever is fresh. In competitive games decided after the sixth inning, that gap functions as real leverage in tonight's MLB action.

Cincinnati Reds vs St. Louis Cardinals Key Insights

  • Greene's 2026 K rate is 14.3 per 9 innings (26 K in 16.1 IP). Winn, Nootbaar, and Burleson have combined for a sub-.450 OPS against him across 34 career plate appearances. The Cardinals' core of the lineup has not solved him, and the conditions tonight favor a dominant strikeout performance.
  • Pallante averaged 2.3 strikeouts per start over his last three outings against a line set at 4.5 K. His 2026 K/9 of 6.4 confirms limited bat-missing ability as a baseline, not just recent bad luck. He does not pitch deep into games and the bullpen behind him is overworked entering tonight.
  • The Cardinals bullpen situation is worse than the box score reflects. O'Brien threw 63 pitches across three recent appearances and Svanson threw 37 on Thursday with no off-day between then and now. If Greene hands a lead to Cincinnati after five innings, the Reds' rested pen closes against a Cardinals bullpen that is running thin on quality arms.
  • Busch Stadium's 0.98 runs factor and 0.95 home run factor, combined with 69-degree temperatures and showers near first pitch, push the environment firmly toward pitchers tonight. Walker's 0 HR in 7 post-break games despite elite exit velocity is a real-time signal that ball carry is suppressed at this park right now.
  • Nathaniel Lowe against Pallante is the clearest individual edge in this game. A .364 average, 1.326 OPS, and 2 home runs across 12 career PA with an escalating trend across seasons. His 2026 OPS in those matchups is 2.500. That kind of consistency is actionable data, not noise.
  • Contrarian angle worth watching: Greene has thrown only 16.1 innings in 2026 and his durability is a genuine unknown. If he exits early, Walker's career numbers against him (.571 AVG, 1.339 OPS in 8 PA from 2023) and the Cardinals' home crowd put St. Louis back in play. The Cardinals -0.5 run line at +102 offers value for bettors skeptical of Greene making it through six innings clean.

Cincinnati Reds vs St. Louis Cardinals Betting Picks

Picks made July 25, 2026 at 05:37 AM ET. Odds shown reflect current market prices.

Reds -1.5 Run Line (+150, MEDIUM)
Reds -1.5 Run Line (+150, MEDIUM): At plus money, this is the most attractive wager in the game if Greene delivers past five innings. His last home start produced 7 innings, no runs, and 12 strikeouts. The Cardinals have averaged 3.5 runs per game since the All-Star break and face a rested Cincinnati pen if St. Louis tries to rally late. A two-run margin is achievable given the pitching gap and the bullpen fatigue differential. The +150 price compensates adequately for Greene's limited 2026 inning count and the durability uncertainty that comes with it.
Under 8.5 Runs (-112, LOW)
Under 8.5 Runs (-112, LOW): Busch Stadium, cool temperatures, showers near first pitch, and a Cardinals offense averaging 3.5 runs since the break all lean toward fewer combined runs. Greene's strikeout rate suppresses the home side and a rested Reds pen closes late. The caveat is honest: Pallante's hittable profile introduces run risk for Cincinnati early, and the market line sits at a point where genuine balance exists. Low confidence is the right call here. The environment supports the Under more than the pitching matchup alone does, and variance is real when a contact-yielding starter is involved.
NRFI (-132)
NRFI (-132): Greene generates early-count swings and misses at a 14-plus K/9 rate in 2026. The Cardinals lineup against him has historically struggled to put the ball in play, with Winn, Nootbaar, and Burleson all posting sub-.500 OPS in career plate appearances. Pallante's 2.65 BB/9 in 2026 shows he limits the first-inning walks that produce early crooked numbers. Cool, damp conditions further suppress first-inning offense by limiting ball carry. The -132 price reflects reasonable market confidence on two starters built to attack hitters from pitch one.
Pallante Under 4.5 Strikeouts (-139, HIGH)
Pallante Under 4.5 Strikeouts (-139, HIGH): This is the highest-conviction prop on the board tonight. Pallante's last three starts: 3 K, 2 K, 2 K. He is averaging 2.3 strikeouts per outing against a line set at 4.5. His 2026 K/9 of 6.4 confirms that limited bat-missing ability is a structural trait, not a temporary slump. The Reds are not a free-swinging lineup that artificially pads strikeout totals for contact pitchers. Pallante would need to nearly double his recent pace to clear this line. The gap between the number and current performance is too wide to ignore at any confidence level.
Hunter Greene Over 6.5 Strikeouts (+114, MEDIUM)
Hunter Greene Over 6.5 Strikeouts (+114, MEDIUM): Greene has cleared 6.5 strikeouts in all three of his most recent starts, including a 7-K performance during a July 4 outing where he gave up 8 runs in 3.1 innings. Even when he is getting hit, the strikeouts arrive. His 2026 rate is 14.3 K/9. Winn, Nootbaar, and Burleson are three likely Cardinals starters with collective sub-.450 OPS against him in career plate appearances. At +114, the market undervalues his ceiling against a lineup that has historically not been able to put his pitches in play. He does not need a perfect outing to reach 7 strikeouts. He needs five or six innings of average Greene.
Masyn Winn Under 0.5 Hits (+132, MEDIUM)
Masyn Winn Under 0.5 Hits (+132, MEDIUM): Winn is 1-for-10 (.100 AVG, 0.200 OPS) in 10 career plate appearances against Greene. That is near-historic futility against one pitcher. His overall 2026 OPS versus right-handed pitching sits at 0.587, below average as a baseline. Greene's elite strikeout rate amplifies that weakness. The market implies only 43.1% probability of a hitless game for Winn, which understates how consistently he has failed to make contact against this specific pitcher. At +132, that pricing gap is worth exploiting.
Nathaniel Lowe Over 0.5 Hits (-196, MEDIUM)
Nathaniel Lowe Over 0.5 Hits (-196, MEDIUM): Lowe against Pallante is the clearest individual matchup edge in this game. He owns a .364 average, 1.326 OPS, and 2 home runs across 12 career PA, with his most recent 2026 appearances against this pitcher producing a 2.500 OPS. He also carries a .800 OPS over the last seven days. The -196 price is steep but reflects appropriate market confidence. This matchup has produced consistent results across multiple seasons and there is no evidence the pattern is reversing. The juice is warranted here.
Alec Burleson Under 1.5 Total Bases (-132, LOW)
Alec Burleson Under 1.5 Total Bases (-132, LOW): Burleson is 2-for-10 (.200 AVG, 0.473 OPS) in 11 career PA against Greene, with no home runs in those matchups. His OPS against Greene declined from 1.000 in 2022 (2 PA), to 0.000 in 2023 (3 PA), to 0.533 in 2024 (6 PA), a downward trajectory across three seasons of data. His overall OPS versus right-handed pitching is strong at .945, but Greene's strikeout arsenal has consistently neutralized that split in career matchups. Low confidence given Burleson's overall power profile and the randomness embedded in small samples, but the career trend supports limited extra-base contact tonight.
Same Game Parlay
Same Game Parlay: Reds ML + Under 8.5 + Greene Over 6.5 K + Winn Under 0.5 Hits: Greene pitching a dominant, high-strikeout game is the engine of this parlay. That single outcome directly suppresses Cardinals offense, which supports the Under, gives Cincinnati a clean path to the moneyline win, and creates the conditions under which Winn goes hitless. These four outcomes are directionally correlated, not independent bets stacked randomly. The Reds winning a low-scoring game with Greene punching out the Cardinals lineup is one coherent scenario, and each leg reinforces the others if that scenario plays out.
Analysis insight — no specific bet associated

Key Players

Batting AverageCIN
Elly De La Cruz
.276Batting Average
SS
Home RunsCIN
Sal Stewart
21Home Runs
1B
Runs Batted InCIN
Sal Stewart
75Runs Batted In
1B
Earned Run AverageCIN
Chase Burns
2.42Earned Run Average
SP
WinsCIN
Chase Burns
12Wins
SP
StrikeoutsCIN
Chase Burns
124Strikeouts
SP
Batting AverageSTL
Jordan Walker
.288Batting Average
RF
Home RunsSTL
Jordan Walker
22Home Runs
RF
Runs Batted InSTL
Jordan Walker
77Runs Batted In
RF
Earned Run AverageSTL
Michael McGreevy
3.07Earned Run Average
SP
WinsSTL
Andre Pallante
10Wins
SP
StrikeoutsSTL
Dustin May
103Strikeouts
SP

Recent Form

Cincinnati Reds
W9-6Colorado Rockies
L8-0Seattle Mariners
W4-2Seattle Mariners
W5-3Seattle Mariners
W4-2St. Louis Cardinals
St. Louis Cardinals
L3-2Los Angeles Angels
L5-1Los Angeles Angels
W1-0Los Angeles Angels
L10-6Arizona Diamondbacks
L4-2Cincinnati Reds

Cincinnati Reds vs St. Louis Cardinals Summary

Environment, matchup, and rest advantage all align in the same direction tonight. Greene is rounding into form with 19 strikeouts in his last 13 innings, pitching against a Cardinals lineup that has collectively failed to barrel him up. Pallante is averaging 2.3 strikeouts per start over his last three outings while his bullpen behind him arrives taxed from Thursday's 10-6 loss with no rest buffer. Busch Stadium on a cool, damp evening pushes the environment toward pitchers. Nathaniel Lowe has a 1.326 OPS against Pallante across 12 career plate appearances with the trend escalating in 2026. These variables do not each independently decide games. Together, they form a pattern that favors Cincinnati clearly enough to act on.

The highest-conviction number is Pallante Under 4.5 strikeouts at -139, where the gap between the line and recent performance (3, 2, 2 K in his last three starts) is the widest I see on tonight's board. The run line at +150 is attractive premium value if Greene stays healthy past the fifth inning. The Reds moneyline at -109 is reasonable given the situational edge. The contrarian case is real and worth respecting: Greene has just 16.1 innings in 2026, and Walker has historically torched him (.571 AVG, 1.339 OPS in 8 PA from 2023). If Greene exits early and Walker's power activates at home, the Cardinals -0.5 run line at +102 comes alive. Manage exposure on the run line accordingly. The situational edge is genuine. So is the durability risk on a pitcher still working back into a full workload.

For the full slate, see our MLB picks today, NRFI picks, and player props.

Head-to-Head History

Season SeriesCIN leads series 1-0
DateMatchupResult
Jul 25, 2026CIN @ STLCINCIN 4-2

Reds vs Cardinals predictions: Greene's 14.3 K/9 meets a taxed STL bullpen. Best bets: Reds ML -109, Pallante Under 4.5 K, Lowe Over 0.5 hits -196.

Frequently Asked Questions

MLBGame PreviewsCincinnati Reds at St. Louis Cardinals